Lipodystrophy is a group of rare conditions characterised by the lack of subcutaneous fat (normal fat storage under the skin). Lipodystrophy can be generalised (total fat loss) or partial (partial fat loss) and familial (inherited) or acquired (not inherited). The inability to store fat under the skin causes fat to be stored in places such as the muscles and liver which leads to severe metabolic complications including insulin resistance, diabetes, dyslipidaemia, heart disease, kidney disease, fatty liver disease and many others. #WorldLipodystrophyDay @LipodystrophyUk
